QIS for Quantum Computing: Why Circuit Optimization Fragments Across QPUs — and What Distributed Outcome Routing Changes

Your variational quantum eigensolver converged beautifully on your lab's 27-qubit device. The noise mitigation strategy you developed over six months reduced gate error by 34%. You publish the paper. Three labs on three continents attempt to replicate it. They fail - not because your result was wrong, but because your noise mitigation strategy was tuned to your hardware's specific decoherence fingerprint. This is quantum computing's synthesis problem. It is not a calibration problem. It is not a hardware problem.