AlphaGenome Deciphers Non-Coding DNA for Gene Regulation

IEEE Spectrum AI
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When AlphaFold solved the protein-folding problem in 2020, it showed that artificial intelligence could crack one of biology’s deepest mysteries: how a string of amino acids folds itself into a working molecular machine. The team at Google DeepMind behind that Nobel Prize-winning platform then turned their lens from from the structure of proteins to how these molecules function in the body. Applying similar machine learning methods, they first developed AlphaMissense, an AI tool for predicting which changes in protein structure are likely to cause disease.