AI RESEARCH

SA-CycleGAN-2.5D: Self-Attention CycleGAN with Tri-Planar Context for Multi-Site MRI Harmonization

arXiv CS.LG

ArXi:2603.17219v1 Announce Type: cross Multi-site neuroimaging analysis is fundamentally confounded by scanner-induced covariate shifts, where the marginal distribution of voxel intensities $P(\mathbf{x})$ varies non-linearly across acquisition protocols while the conditional anatomy $P(\mathbf{y}|\mathbf{x})$ remains constant. This is particularly detrimental to radiomic reproducibility, where acquisition variance often exceeds biological pathology variance.