Beyond Expression Similarity: Contrastive Learning Recovers Functional Gene Associations from Protein Interaction Structure

ArXi:2603.20955v1 Announce Type: cross The Predictive Associative Memory (PAM) framework posits that useful relationships often connect items that co-occur in shared contexts rather than items that appear similar in embedding space. A contrastive MLP trained on co-occurrence annotations--Contrastive Association Learning (CAL)--has improved multi-hop passage retrieval and discovered narrative function at corpus scale in text.