AI RESEARCH
Fair splits flip the leaderboard: CHANRG reveals limited generalization in RNA secondary-structure prediction
arXiv CS.LG
•
ArXi:2603.22330v1 Announce Type: cross Accurate prediction of RNA secondary structure underpins transcriptome annotation, mechanistic analysis of non-coding RNAs, and RNA therapeutic design. Recent gains from deep learning and RNA foundation models are difficult to interpret because current benchmarks may overestimate generalization across RNA families.