AI RESEARCH
Cross-Modal Knowledge Distillation for PET-Free Amyloid-Beta Detection from MRI
arXiv CS.CV
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ArXi:2604.12574v1 Announce Type: new Detecting amyloid-$\beta$ (A$\beta$) positivity is crucial for early diagnosis of Alzheimer's disease but typically requires PET imaging, which is costly, invasive, and not widely accessible, limiting its use for population-level screening. We address this gap by proposing a PET-guided knowledge distillation framework that enables A$\beta$ prediction from MRI alone, without requiring non-imaging clinical covariates or PET at inference.