AI RESEARCH

Continual Learning for fMRI-Based Brain Disorder Diagnosis via Functional Connectivity Matrices Generative Replay

arXiv CS.LG

ArXi:2604.14259v1 Announce Type: cross Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing diagnostic models are trained either on a single site or under full multi-site access, making them unsuitable for real-world scenarios where clinical data arrive sequentially from different institutions. This results in limited generalization and severe catastrophic forgetting.