AI RESEARCH
Scalable Agentic Reasoning for Designing Biologics Targeting Intrinsically Disordered Proteins
arXiv CS.AI
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ArXi:2512.15930v2 Announce Type: replace-cross Intrinsically disordered proteins (IDPs) represent crucial therapeutic targets due to their significant role in disease -- approximately 80\% of cancer-related proteins contain long disordered regions -- but their lack of stable secondary/tertiary structures makes them "undruggable