AI RESEARCH

Secure On-Premise Deployment of Open-Weights Large Language Models in Radiology: An Isolation-First Architecture with Prospective Pilot Evaluation

arXiv CS.CL

ArXi:2604.22768v1 Announce Type: cross Purpose: To design, implement, evaluate, and report on the regulatory requirements of a self-hosted LLM infrastructure for radiology adhering to the principle of least privilege, emphasizing technical feasibility, network isolation, and clinical utility. Materials and Methods: The isolation-first, containerized LLM inference stack relies on strict network segmentation, host-enforced egress filtering, and active isolation monitoring preventing unauthorized external connectivity.