AI RESEARCH

Dino-NestedUNet: Unlocking Foundation Vision Encoders for Pathology Tumor Bulk Segmentation via Dense Decoding

arXiv CS.CV

ArXi:2605.00894v1 Announce Type: new Vision foundation models (VFMs), such as DINOv3, provide rich semantic representations that are promising for computational pathology. However, many current adaptations pair frozen VFMs with lightweight decoders, creating a capacity mismatch that often limits boundary fidelity for infiltrative tumor bulk segmentation. This paper presents Dino-NestedUNet, a framework that couples a pre-trained DINOv3 encoder with a Nested Dense Decoder.