AI RESEARCH

Tree-Conditioned Edit Flows for Ancestral Sequence Reconstruction

arXiv CS.LG

ArXi:2605.04119v1 Announce Type: cross Ancestral sequence reconstruction (ASR) aims to infer extinct protein sequences at internal nodes of a phylogenetic tree. Classical ASR methods are typically based on continuous-time Marko substitution models, but they treat sites largely independently and handle insertions and deletions only weakly or not at all. We