AI RESEARCH
Learning Multi-Relational Graph Representations for DNA Methylation-Based Biological Age Estimation
arXiv CS.AI
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ArXi:2605.07175v1 Announce Type: cross Aging clocks aim to estimate biological age, a measure of physiological state distinct from chronological age, from observable biomarkers, and are widely used for health assessment and disease analysis. DNA methylation is a particularly informative biomarker due to its stability and strong association with aging, and recent learning-based approaches have improved predictive performance. However, most existing methods treat CpG sites as independent features, overlooking the complex and heterogeneous biological relationships among them.