AI RESEARCH
ContextFlow: Context-Aware Flow Matching For Trajectory Inference From Spatial Omics Data
arXiv CS.LG
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ArXi:2510.02952v3 Announce Type: replace Inferring trajectories from longitudinal spatially-resolved omics data is fundamental to understanding the dynamics of structural and functional tissue changes in development, regeneration and repair, disease progression, and response to treatment. We propose ContextFlow, a novel context-aware flow matching framework that incorporates prior knowledge to guide the inference of structural tissue dynamics from spatially resolved omics data.