AI RESEARCH
SpatialMAGIC: A Hybrid Framework Integrating Graph Diffusion and Spatial Attention for Spatial Transcriptomics Imputation
arXiv CS.LG
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ArXi:2603.06780v1 Announce Type: new Spatial transcriptomics (ST) enables mapping gene expression with spatial context but is severely affected by high sparsity and technical noise, which conceals true biological signals and hinders downstream analyses. To address these challenges, SpatialMagic was proposed, which is a hybrid imputation model combining MAGIC-based graph diffusion with transformer-based spatial self-attention.