ViroGym: Realistic Large-Scale Benchmarks for Evaluating Viral Proteins

ArXi:2603.06740v1 Announce Type: cross Protein language models (pLMs) have shown strong potential in prediction of the functional effects of missense variants in zero-shot settings. Despite this progress, benchmarking pLMs for viral proteins remains limited and systematic strategies for integrating in silico metrics with in vitro validation to guide antigen and target selection are underdeveloped. Here, we